Teesside MP Simon Clarke has resigned from the federal government for private causes.
In his letter to Boris Johnson, the Middlesbrough South and East Cleveland MP talked about “balancing my own life against the demands of office”.
He was appointed to the Ministry of Housing, Communities and Local Government in February after transferring from the Treasury.
Mr Clarke will proceed as an MP and says he hopes to return sooner or later.
Writing to the Prime Minister, he stated: “I would not have made this decision unless I believed it was of the utmost importance.”
He added: “It has been a privilege to serve as a minister in your administration.”
As minister for regional progress and native authorities, his duties included the native authority resilience discussion board’s Covid-19 response and devolution.
BBC Look North political correspondent Luke Walton stated: “This is a significant announcement and will come as a surprise to supporters and opponents alike.
“Simon Clarke was extensively seen as a Government excessive flyer, in a key job.”