According to an ICMR research, a single dose of Bharat Biotech’s Covaxin in beforehand COVID-19-infected people elicited an analogous antibody response as was achieved with two doses of the vaccine and not using a earlier historical past of the illness.
The research was printed within the Indian Journal of Medical Research on Saturday.
“If our preliminary findings are confirmed in larger population studies, a single dose of BBV152 vaccine may be recommended to previously confirmed SARS-CoV-2 infected individuals so that nave individuals can benefit greatly from limited vaccine supplies.” can do,” it stated. .
India’s first indigenous COVID-19 vaccine Covaxin, codenamed BBV152, was permitted by the federal government in January for emergency use. Two doses are given at intervals of 4 to 6 weeks.
Study to look at SARS-CoV-2-specific antibody responses on day zero (baseline, earlier than vaccination), day 28 plus/minus two days after the primary dose (month 1) and day 56 plus/minus two days after was carried out to analyze. First dose (month 2) of BBV152 in a gaggle of healthcare professionals in addition to frontline staff.
The antibody response of people with confirmed pre-vaccination SARSCoV-2 an infection was in contrast with these of people with no prior proof of an infection.
As part of the research, blood samples had been collected from 114 healthcare professionals and frontline staff receiving Covaxin at vaccination facilities in Chennai from February to May 2021.
“Overall, good vaccine-induced antibody responses were observed in previously SARS-CoV-2-infected individuals, except for two who had received a single dose of BBV152 vaccine, with antibody responses observed after a two-dose vaccination course. was similar. infection-naive individuals,” the research stated.
“Our results in a diverse group of healthcare professionals and frontline workers lend support to previous studies (albeit primarily focused on mRNA vaccines) that found increased levels of SARS-CoV-2 binding and neutralizing antibodies that could are present after a single vaccine dose in people already infected. The levels are equal to those seen after two doses in individuals and without prior infection,” it added.
The research presents proof in help of public health-oriented and immunologically sustained vaccine methods.
.
With inputs from TheIndianEXPRESS
